非小细胞肺癌,放疗系列研究汇总(潜在可手术Ⅲ期)
非小细胞肺癌,术后放疗系列研究汇总
非小细胞肺癌,放疗系列研究汇总(不可手术Ⅲ期)
全文概要
单站N2
1. 一项Meta分析:与单纯手术组比较,新辅助化疗组的OS显著延长
多站N2(治疗存在分歧)
2. EORTC08941研究:诱导化疗后手术对比放疗,OS无差异
3. INT0139研究:诱导放化疗后手术对比根治性放化疗,OS无差异
4. SAKK研究:新辅助化疗后手术对比新辅助序贯放化疗后手术,OS无差异
5. ESPATUE研究:新辅助化疗+序贯同步放化疗后根治性手术对比新辅助化疗后续贯根治性放化疗,OS无差异
6. GLCCG 研究:新辅助化疗+手术+放疗 vs.新辅助化疗+同步放化疗+手术,OS无差异
肺上沟瘤
7. 一项研究:新辅助同步放化疗后进行手术治疗,5年生存率为44%
CSCO丨可手术IIIA或IIIB(T3N2M0)期NSCLC的治疗
总体OS
III期OS
01
诱导化疗后手术对比放疗
02
诱导放化疗后手术对比根治性放化疗
03
新辅助化疗后手术对比新辅助序贯放化疗后手术
04
新辅助化疗+序贯同步放化疗后根治性手术对比新辅助化疗后续贯根治性放化疗
05
新辅助化疗+手术+放疗 vs.新辅助化疗+同步放化疗+手术
01
对于潜在可切除的肺上沟瘤,推荐新辅助同步放化疗后进行手术治疗,手术一般在放疗结束后3~6 周内进行。
潜在预后因素相对风险
参考文献
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