国内团队：花生或是一个好零食 | 热心肠日报
在中国成年人惯性零食摄入中，利用花生代替白米条，可以改善代谢综合征风险：随机对照实验
10.1093/ajcn/nqaa307
11-20, Article
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BackgroundObservational studies have suggested that intake of nuts is associated with lower risk of cardiometabolic diseases, whereas refined grain consumption has been linked to higher risk. Little is known about whether substituting white rice, a refined grain, with nuts may confer benefit among adults at high risk of cardiometabolic diseases.ObjectivesWe aimed to evaluate isocaloric substitution of peanuts for white rice bars as snacks on changes in fasting glucose, lipid profile, body weight, as well as changes in metabolic syndrome (MetS) status among participants with MetS or at risk of MetS.MethodsThis parallel-arm randomized controlled trial included 224 participants either with MetS (according to the International Diabetes Federation criteria for Chinese adults, n = 163) or at risk of MetS (central obesity plus 1 additional MetS risk factor, n = 61). Participants were randomly assigned to either the peanut arm (56 g/d as snacks, n = 113) or the control arm (isocaloric white rice bars, n = 111) for 12 wk.ResultsA total of 209 participants (93.3%) completed the 12-wk intervention with a compliance rate > 85% among all participants. No between-group differences were found for improvements in fasting glucose, HDL cholesterol, waist circumference, and body weight. Participants in the peanut group had a significantly higher MetS reversion rate (no longer meeting MetS criteria after the 12-wk trial) than those in the control group (RR: 2.33; 95% CI: 1.10, 4.89; P = 0.026).ConclusionsIncluding peanuts as a snack in the habitual diet in place of a refined-grain snack did not significantly change glycemic or lipid parameters, but improved overall MetS risk without promoting weight gain among Chinese adults at high risk of cardiometabolic diseases. Further larger-scale trials are needed to confirm these findings and elucidate underlying biological mechanisms.
First Authors:
Di Wang,Liang Sun,Xiaoran Liu
Correspondence Authors:
Vasanti Malik,Xu Lin
All Authors:
Di Wang,Liang Sun,Xiaoran Liu,Zhenhua Niu,Shuangshuang Chen,Lixin Tang,He Zheng,Xiafei Chen,Huaixing Li,Ling Lu,Vasanti Malik,Xu Lin