Beirut反应

在碱性条件下由苯并呋咱氧化物制备喹喔啉-1,4-二氧化物的反应。

反应机理

反应实例

特殊的Beirut反应的机理

参考文献

1. Haddadin, M. J.; Issidorides, C. H. Heterocycles 1976, 4, 767-816. The authors named the reaction after the city where it was discovered, Beirut, the capital of Lebanon. 贝鲁特（Beirut），黎巴嫩首都， 此反应的发现者以发现此反应的城市命名反应。

2. Gaso, A.; Boulton, A. J. In Advances in Heterocyclic Chem.; Vol. 29, Katritzky, A. R.; Boulton, A. J., eds.; Academic Press Inc.: New York, 1981, 251. (Review).

3. Vega, A. M.; Gil, M. J.; Fernández-Alvarez, E. J. Heterocycl. Chem. 1984, 21, 1271.

4. Atfah, A.; Hill, J. J. Chem. Soc., Perkin Trans. 1 1989, 221-224.

5. Haddadin, M. J.; Issidorides, C. H. Heterocycles 1993, 35, 1503-1525.

6. El-Abadelah, M. M.; Nazer, M. Z.; El-Abadla, N. S.; Meier, H. Heterocycles 1995, 41, 2203-2219.

7. Takabatake, T.; Miyazawa, T.; Kojo, M.; Hasegawa, M. Heterocycles 2000, 53,

2151-2162.

8. Panasyuk, P. M.; Mel’nikova, S. F.; Tselinskii, I. V. Russ. J. Org. Chem. 2001, 37, 892.

9. Turker, L.; Dura, E. Theochem 2002, 593, 143-147.

10. Tinsley, J. M. Beirut Reaction in Name Reactions in Heterocyclic Chemistry, Li, J. J., Ed.; Wiley: Hoboken, NJ, 2005, 504-509. (Review).

11. Sun, T.; Zhao, W.-J.; Hao, A.-Y.; Sun, L.-Z. Synthesis 2011, 41, 3097-3105.

12. Haddadin, M. J.; El-Khatib, M.; Shoker, T. A.; Beavers, C. M.; Olmstead, M. M.; Fettinger, J. C.; Farber, K. M.; Kurth, M. J. J. Org. Chem. 2011, 76, 8421-8427.

编译自：J.J. Li, Name Reactions: A Collection of Detailed Mechanisms and Synthetic Applications,  Beirut reaction，page 42-43.