关注IBD中的肠道真菌及病毒（综述） | 热心肠日报
Effects of Intestinal Fungi and Viruses on Immune Responses and Inflammatory Bowel Diseases
肠道真菌与病毒对IBD中的免疫应答的影响
10.1053/j.gastro.2020.06.100
12-18, Review
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The intestinal microbiota comprises diverse fungal and viral components, in addition to bacteria. These microbes interact with the immune system and affect human physiology. Advances in metagenomics have associated inflammatory and autoimmune diseases with alterations in fungal and viral species in the gut. Studies of animal models have found that commensal fungi and viruses can activate host-protective immune pathways related to epithelial barrier integrity, but can also induce reactions that contribute to events associated with inflammatory bowel disease. Changes in our environment associated with modernization and the COVID-19 pandemic have exposed humans to new fungi and viruses, with unknown consequences. We review the lessons learned from studies of animal viruses and fungi commonly detected in the human gut and how these might affect health and intestinal disease.
First Authors:
Iliyan D Iliev
Correspondence Authors:
Iliyan D Iliev,Ken Cadwell
All Authors:
Iliyan D Iliev,Ken Cadwell