欧洲临床营养和代谢学会肝病指南 / 开普饭

　　2019年4月，欧洲肠外肠内营养学会（欧洲临床营养和代谢学会）官方期刊《临床营养》正式发表德国德绍市立医院、莱比锡大学、霍恩海姆大学、英国伦敦大学国王学院、美国克利夫兰医院、意大利罗马大学、新西兰奥克兰大学起草的欧洲临床营养和代谢学会肝病临床营养指南，全文共37页。2019年5月，南开大学附属天津市第三中心医院暨天津医科大学三中心临床学院肖慧娟、齐玉梅、韩涛对该指南进行摘译和审校，发表于《临床肝胆病杂志》。

译文参见：临床肝胆病杂志. 2019;35(5):968-972.

原文参见：Clin Nutr. 2019 Apr;38(2):485-521.

ESPEN guideline on clinical nutrition in liver disease.

Plauth M, Bernal W, Dasarathy S, Merli M, Plank LD, Schütz T, Bischoff SC.

Municipal Hospital of Dessau, Dessau, Germany; King's College Hospital, London, United Kingdom; Cleveland Clinic, Cleveland, OH, USA; Sapienza University of Rome, Rome, Italy; University of Auckland, Auckland, New Zealand; Leipzig University Medical Centre, Leipzig, Germany; University of Hohenheim, Stuttgart, Germany.

This update of evidence-based guidelines (GL) aims to translate current evidence and expert opinion into recommendations for multidisciplinary teams responsible for the optimal nutritional and metabolic management of adult patients with liver disease. The GL was commissioned and financially supported by ESPEN. Members of the guideline group were selected by ESPEN. We searched for meta-analyses, systematic reviews and single clinical trials based on clinical questions according to the PICO format. The evidence was evaluated and used to develop clinical recommendations implementing the SIGN method. A total of 85 recommendations were made for the nutritional and metabolic management of patients with acute liver failure, severe alcoholic steatohepatitis, non-alcoholic fatty liver disease, liver cirrhosis, liver surgery and transplantation as well as nutrition associated liver injury distinct from fatty liver disease. The recommendations are preceded by statements covering current knowledge of the underlying pathophysiology and pathobiochemistry as well as pertinent methods for the assessment of nutritional status and body composition.

KEYWORDS: Acute liver failure; Alcoholic steatohepatitis; Cirrhosis; Fatty liver disease; Sarcopenia; Transplantation

PMID: 30712783

DOI: 10.1016/j.clnu.2018.12.022