284.Malignant Mesothelioma（1）（恶性间皮瘤）

每天朗读一段医学影像学英语文章

History

An 88-year-old female presents with dyspnea.

Diagnosis

Malignant Mesothelioma

Discussion

Malignant mesothelioma is the most common primary pleural neoplasm associated with asbestos exposure. The patient usually presents with dyspnea, chest pain, cough and weight loss. As the disease progresses, it often extends into the pulmonary parenchyma, chest wall, mediastinum and diaphragm. It is almost always fatal with median survival of 11 months. Factors associated with a reduced survival time include intrathoracic lymph node metastases, distant metastases, and extensive pleural involvement.

Butchart Staging for Malignant Mesothelioma:

Stage Findings

-Tumor confined to the ipsilateral pleura, lung, or pericardium

-Tumor invading the chest wall or mediastinal structures, or metastasis to thoracic lymph nodes

-Tumor extending through the diaphragm to involve the peritoneum or extra-thoracic lymph node metastasis

-Distant hematogenous metastasis

Notes:

1. mesothelioma [ˌmesˌmezəˌθi:li:'oʊmə] n. 间皮瘤

2. dyspnea [dɪsp'ni:ə] n. 呼吸困难

3. pleural ['plʊərə] adj. 胸腔; 肋膜的，胸膜的

4. asbestos [æsˈbɛstəs, æz-] n. 石棉

5. parenchyma [pə'reŋkɪmə] n. 实质

6. mediastinum [ˌmi:dɪæs'taɪnəm] n. （胸腔） 纵隔

7. diaphragm [ˈdaɪəˌfræm] n. 膈

8. intrathoracic [ɪntrəθə'ræsɪk] adj. 胸内的

9. ipsilateral [ɪpsɪ'lætərəl] adj. 身体的同侧的

10. pleura [ˈplʊrə] n. 肋膜，胸膜

11. pericardium [ˌperɪ'kɑ:dɪrm] n. 围心，心包膜

12. peritoneum [ˌpɛrɪtnˈiəm] n. 腹膜

13. hematogenous [ˌhemə'tɒdʒənəs] adj. 造血的

来源：每天朗读一段医学影像学英语文章

圈主

深圳市人民医院放射科副主任医师杨敏洁

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