一文读懂IBD与菌群的密切关联（综述）
IBD与菌群：犯罪现场搜寻线索
10.1053/j.gastro.2020.09.056
11-26, Review
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Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial, immunological, and genetic factors. Alterations in the gut microbiota have been associated with development and progression of IBD, but it is not clear which populations of microbes are involved or how they might contribute to IBD. We review the genetic and environmental factors affecting the gut microbiota, the roles of gut microbes and their bioproducts in the development and clinical course of IBD, and strategies by which microbiome-based therapies can be used to prevent, manage, and eventually cure IBD. We discuss research findings that help bridge the gap between the basic sciences and clinical application.
First Authors:
Mirae Lee
Correspondence Authors:
Eugene B Chang
All Authors:
Mirae Lee,Eugene B Chang