送给你100+篇精选的单细胞测序文献

几天前和几个在做数据挖掘的好朋友聊天，讨论到接下来数据挖掘的热点可能会怎样变化？我们觉得可能会朝着单细胞测序和非肿瘤倾斜一部分。因为目前常规的TCGA的各种套路已经有些过于套路的感觉了；肿瘤的简单数据挖掘还是慢慢要回归到有实验的验证层面。花了一周左右时间，筛了2019年以来能在PubMed检索到的单细胞测序文章，最后经过挑选以后，选出来了100+篇；我们的小编团队已经开始行动了！我们承诺在一年内整理推完所有的单细胞测序推文！如果您觉得有很好的文献，请私信推荐给科研菌哟！长按识别二维码，关注科研菌，后台回复“单细胞文献”，即可获取单细胞文献向←拖拽表格查看完整表格No.Title1Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease2A benchmark of batch-effect correction methods for single-cell RNA sequencing data3A cell atlas of human thymic development defines T cell repertoire formation4A cellular census of human lungs identifies novel cell states in health and in asthma5A human liver cell atlas reveals heterogeneity and epithelial progenitors6Accurate estimation of cell-type composition from gene expression data7An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates8An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics9An immune-cell signature of bacterial sepsis10Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis11B cells and tertiary lymphoid structures promote immunotherapy response12Benchmarking principal component analysis for large-scale single-cell RNA-sequencing13Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging14Cell-type-specific signaling networks in heterocellular organoids15Cellular Heterogeneity and Lineage Restriction during Mouse Digit Tip Regeneration at Single-Cell Resolution16Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution17Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL18Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy19Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease20Combination of PD1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer21Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing22Decoding the development of the human hippocampus23Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics24Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency25Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics26Dynamic Interstitial Cell Response during Myocardial Infarction Predicts Resilience to Rupture in Genetically Diverse Mice27Functional heterogeneity of lymphocytic patterns in primary melanoma dissected through single-cell multiplexing28Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments29Genomic programming of IRF4-expressing human Langerhans cells30Glial cell diversity and methamphetamine-induced neuroinflammation in human cerebral organoids31Heterogeneity of Satellite Cells Implicates DELTA1_NOTCH2 Signaling in Self-Renewal32Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome33Identification of region-specific astrocyte subtypes at single cell resolution34Immune Landscape of Viral- and Carcinogen-Driven Head and Neck Cancer35Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma36In Vitro and In Vivo Development of the Human Airway at Single-Cell Resolution37In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes38Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population39Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis40Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas41Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies42Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis43Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors44Memory B Cell Activation, Broad Anti-influenza Antibodies, and Bystander Activation Revealed by Single-Cell Transcriptomics45Metabolic landscape of the tumor microenvironment at single cell resolution46Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways47Multi-omics profiling of mouse gastrulation at single-cell resolution48Organoid single cell profiling identifies a transcriptional signature of glomerular disease49Organoid single-cell genomic atlas uncovers human-specific features of brain development50Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma51Peripheral T cell expansion predicts tumour infiltration and clinical response52Platform Effects on Regeneration by Pulmonary Basal Cells as Evaluated by Single-Cell RNA Sequencing53Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing54Resolving medulloblastoma cellular architecture by single-cell genomics55Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state56Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches57Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation58Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal Development59Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration60Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage Relationships61Single-Cell Multi-omic Integration Compares and Contrasts Features of Brain Cell Identity62Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney63Single-Cell Reconstruction of Progression Trajectory Reveals Intervention Principles in Pathological Cardiac Hypertrophy64Single-Cell Signature Explorer for comprehensive visualization of single cell signatures across scRNA-seq datasets65Single-Cell Transcriptome Analysis Maps the Developmental Track of the Human Heart66Single-Cell Transcriptome Atlas of Murine Endothelial Cells67Single-Cell Transcriptomic Atlas of Primate Ovarian Aging68Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures69Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory Response70Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration71Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression72Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program73Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects74Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells75Single-cell analysis of olfactory neurogenesis and differentiation in adult humans76Single-cell analysis reveals T cell infiltration in old neurogenic niches77Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds78Single-cell analysis reveals new evolutionary complexity in uveal melanoma79Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids80Single-cell connectomic analysis of adult mammalian lungs81Single-cell immune landscape of human atherosclerotic plaques82Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function83Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis84Single-cell transcriptomic analysis of Alzheimer’s disease85Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer86Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration87Single-cell transcriptomics of blood reveals a natural killer cell subset depletion in tuberculosis88Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease89A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart90Spatiotemporal single-cell analysis of gene expression in the mouse suprachiasmatic nucleus91Surface protein imputation from single cell transcriptomes by deep neural networks92Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain93The Molecular Anatomy of Mouse Skin during Hair Growth and Rest94The art of using t-SNE for single-cell transcriptomics95The bone marrow microenvironment at single-cell resolution96The immune cell landscape in kidneys of patients with lupus nephritis97The single-cell pathology landscape of breast cancer98Tracing tumorigenesis in a solid tumor model at single-cell resolution99Trajectory-based differential expression analysis for single-cell sequencing data100Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity101Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution102Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing103Transcriptional dynamics of hepatic sinusoid‐associated cells after liver injury104Using single-cell technologies to map the human immune system — implications for nephrology105scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy科研菌始终都在，陪你度过漫漫科研路希望志同道合的小伙伴就像科研“菌”一样不断裂变，越来越多