左氧氟沙星、环丙沙星......氟喹诺酮类竟可引发主动脉夹层?
但是,氟喹诺酮类还会引起主动脉瘤/夹层!
引起动脉瘤/夹层的机理是什么?
主动脉瘤/夹层有何危害?
哪些人群应避免使用?
临床还能用吗?
总结
氟喹诺酮类抗菌谱广,是临床常用的抗菌药物;
氟喹诺酮类可导致罕见但严重的不良反应:主动脉瘤/夹层;
主动脉瘤、老年患者等高风险人群应尽量避免使用氟喹诺酮类;
处方抗生素应权衡利弊,严格掌握适应证与禁忌证。
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