发纯生信SCI，期刊主编一定让我上传伦理资料，该如何回复？
一般做纯生信数据挖掘，基本离不开这两个数据库：TCGA、GEO。按道理，涉及到人或者动物的研究都要上传伦理资料的，但是做纯生信数据挖掘，病人数据都是从数据库上下载的，没有涉及到伦理问题，故不用上传伦理资料。
不过有些期刊主编并不清楚你的数据是怎么样来的，他看到你的研究涉及到病人，就会让你提交伦理资料。为了减少这些麻烦，你最好就在文章中作出如下声明：
DisclosureTCGA and GEO belong to public databases. The patients involved in the database have obtained ethical approval. Users can download relevant data for free for research and publish relevant articles. Our study is based on open source data, so there are no ethical issues and other conflicts of interest.
有时候就算你在文章中作了上面的声明，期刊主编有可能仍然你需要提交伦理资料（有可能他不理解或者没有看到），不然文章就不送审。遇到这种情况，自己需要认真地进行解释，可以找一篇TCGA这样的公共数据库挖掘的文章发给他看，说明自己的研究跟这篇文章都是利用OA数据库的数据，没有涉及到伦理问题，也可以发送下面这段话进行解释：
The Cancer Genome Atlas (TCGA), a landmark cancer genomics program, molecularly characterized over 20,000 primary cancer and matched normal samples spanning 33 cancer types. This joint effort between NCI and the National Human Genome Research Institute began in 2006, bringing together researchers from diverse disciplines and multiple institutions.Over the next dozen years, TCGA generated over 2.5 petabytes of genomic, epigenomic, transcriptomic, and proteomic data. The data, which has already led to improvements in our ability to diagnose, treat, and prevent cancer, will remain publicly available for anyone in the research community to use.（https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga）
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