Current Opinion in Plant Biology|光调控植物前 mRNA的剪接

红光/远红光吸收光敏色素（phy）家族光感受器感知的光信号在整个生命周期中调节植物的生长发育。光敏色素通过在转录水平和转录后水平控制基因表达来调节光触发的生理反应。最近大规模的RNA-seq研究已经证实phys通过调节前mRNA剪接来改变转录物的多样性。此外，利用正向遗传学和蛋白质-蛋白质相互作用研究，已经鉴定了来自不同物种的几种phy相互作用剪接因子/调节因子，它们调节光调节的前mRNA剪接。在这篇文章中，我们总结了我们目前对phys在光介导的前mRNA剪接中的作用的理解，以及phys如何参与基因表达的调控以促进光形态发生。

Light signal perceived by the red/far-red absorbing phytochrome (phy) family of photoreceptors regulates plant growth and development throughout the life cycle. Phytochromes regulate the light-triggered physiological responses by controlling gene expression both at the transcriptional and post-transcriptional levels. Recent large-scale RNA-seq studies have demonstrated the roles of phys in altering the global transcript diversity by modulating the pre-mRNA splicing in response to light. Moreover, several phy-interacting splicing factors/regulators from different species have been identified using forward genetics and protein–protein interaction studies, which modulate the light-regulated pre-mRNA splicing. In this article, we summarize our current understanding of the role of phys in the light-mediated pre-mRNA splicing and how that contributes to the regulation of gene expression to promote photomorphogenesis.

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